Indicator-BIO of RUSNANO FIEP Start-Up with New Chips and Reagents of FRCC PCM FMBA Detects Coronavirus in 15 Minutes

10 April 2020

The Federal Research and Clinical Centre of Physical-Chemical Medicine (FRCC PCM) of the Federal Medical and Biological Agency (FMBA) presented new chips and reagents for the Indicator-BIO analyser. They allow detecting, within 15 minutes, dangerous viruses, including the novel coronavirus COVID-19, in biological fluids. The Indicator-BIO device was developed by specialists from Troitsk Engineering Centre, part of TechnoSpark Group, a subsidiary of the RUSNANO Group’s Fund for Infrastructure and Educational Programs (FIEP). Earlier, the Indicator-BIO was presented to Veronika Skvortsova, FMBA head.

The main advantage of the model of the Indicator-BIO analyser presented by RUSNANO earlier was its ability to work with different reagents. It was due to the use of new reagents promptly developed by Russian specialists engaged by FMBA that the time of obtaining the analysis result was halved.

RUSNANO Group is ready to use the full potential of developers and engineers of their companies to fight the COVID-19 pandemic.

Portable device
The BIO-Indicator for the detection of viruses

Indicator-BIO mobile device for detection of infections
Photo: Aleksandr Korneev

“Nowadaya, PCR diagnostics is the fastest and most reliable method for diagnosing infectious diseases. Troitsk Nanocentre managed to develop a device that not only dramatically reduced the time required for analysis, literally down to 15 minutes, but also does not require a specially equipped laboratory,” said Anatoly Chubais, Chairman of the Board of Management Company RUSNANO and FIEP.

“We understand the challenge we face today as researchers and developers, and how much we need extremely accurate, fast and simple rapid analysers. In response to this challenge, in just a couple of weeks we and our colleagues at PCM FMBA have found a way to simplify and speed up the procedure of bio-material preparation and subsequent analysis to 15-20 minutes. Our device has almost no competitors in this mobile class, especially considering the cost of analysis. The device and reagents will soon get a registration certificate of a medical device,” said Evgeny Gorsky, General Director of Troitsk Engineering Centre.

“In today’s crisis situation it is important for us not only to increase speed of the analysis for COVID-19 which has become possible due to our device. The speed of launching the production of this equipment critical in the fight against the virus is an equally crucial factor. While one of our start-up developers is testing and improving the device, another start-up is launching the production of optics with the relevant coating for it, the third is professionally assisting with documentation for obtaining the registration certificate, the fourth is finishing the interface design, and the fifth, without waiting for the completion of formal procedures, is working with potential suppliers on delivery terms of components for batch production of the device. The system of division of labour for production of new technological products created by TechnoSpark has worked for the last eight years as a kind of innovation conveyor, quickly and productively,” noted Denis Kovalevich, General Director of TechnoSpark.

Let us recall that the Indicator-BIO analyser uses the polymerase chain reaction (PCR), a highly accurate molecular and genetic diagnosis method, and is capable of identifying up to four different types of pathogen simultaneously. Also, a range of test systems in microfluid cartridge format were developed for the device, including tests capable of identifying the novel SARS-CoV-2 coronavirus.

Additional information

Reference

The Fund for Infrastructure and Educational Programs was established in 2010 in accordance with Federal Law No. 211-FZ “On reorganization of the Russian Corporation of Nanotechnologies.” The Fund aims to develop the innovative infrastructure in the sphere of nanotechnology and implement the educational and infrastructure programs already started by RUSNANO.

The supreme collegial management body of the Fund is the Supervisory Board. Under the Fund’s Charter, the competence of the Supervisory Council, in particular, includes the issues of determining the priority directions of the Fund’s activity, as well as its strategy and budget. The Chairman of the Fund’s Executive Board, the collegial management body, is the Chairman of the Board of Management Company RUSNANO LLC Anatoly Chubais; the Chief Executive Officer of the Fund is Andrey Svinarenko.

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The TechnoSpark Group of Companies, a part of the investment network of the Fund for Infrastructure and Educational Programs, is involved in all aspects of venture creation: from establishing a start-up to its sale. The TechnoSpark Group of Companies is in the hardware industry, working in areas, such as robotics in logistics, energy storage systems, hi-tech medical equipment, diamond optics, braided composites, optical and industrial surfaces, genomics, industrial microbiology, thin-film integrated photovoltaics, additive technologies and flexible electronics. The Group of Companies is in first place according to the National rating of Russia’s most effective technology parks and was included in the National Rating of Russian Fast-growing Technology Companies, TechUp 2019. It is also a part of the community of startup studios, the Global Startup Studio Network (GSSN).

For more information about the company, visit technospark.ru